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Schematic diagram showing involvement of multiple enzymes/proteins in regulation of stringent response and other functions in V. cholerae. During amino acid starvation RelA is activated and synthesizes (p)ppGpp, while fatty acid or glucose starvation induces activation of SpoT and RelV, which also synthesize (p)ppGpp. (p)ppGpp with the help of DksA induces stringent response.
