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. Author manuscript; available in PMC: 2012 Apr 15.
Published in final edited form as: Bioorg Med Chem. 2011 Mar 12;19(8):2582–2588. doi: 10.1016/j.bmc.2011.03.017

Scheme 2.

Scheme 2

Reagents and conditions: (a) phenyl acetic acid, EDC, HOBt, DIEA, DMF, room temp; (b) benzoic acid, EDC, HOBt, DIEA, DMF, room temp.; (c) 3-phenylpropanoic acid, EDC, HOBt, DIEA, DMF, room temp.; (d) trans cinnamic acid, EDC, HOBt, DIEA, DMF, room temp.