TABLE 2.
Chemotaxis analysis of neutrophils
| Experiment and strain | Chemotaxis
resultsa
|
|
|---|---|---|
| Proportion (%) of neutrophils | No. (%) of migrating neutrophils | |
| Casein induction | ||
| BALB/c | 54 | 1.4 × 104 (26) |
| γ-KO | 56 | 0.8 × 104 (14)b |
| 5-KO | 52 | 0.7 × 104 (13)b |
| γ/5-KO | 51 | 0.8 × 104 (14)b |
| L. sigmodontis infection | ||
| BALB/c | 36.5 | 2.9 × 104 (82) |
| γ-KO | 21.5 | 0.3 × 104 (13)b,c |
| 5-KO | 17 | 0.7 × 104 (39)b |
| γ/5-KO | 16.5 | 0.3 × 104 (18)b,c |
a
The number of cells used as input for each experiment and strain was 105. Cells were taken from the peritoneal cavity of uninfected mice subjected to casein induction or from the thoracic cavity of mice infected with L. sigmodontis.
b
Significantly different from results for BALB/c control mice (P < 0.05).
c
Significantly different from results for 5-KO mice (P < 0.05).