TABLE 1.
Evaluation of protective immunity in C3H mice actively immunized with different recombinant proteins and challenged with syringe- or tick-borne B. burgdorferi
| Immunogen | No. of mice
positive/no. of mice testeda
|
|
|---|---|---|
| Syringe challenge | Tick challenge | |
| GT (negative control) | 5/5 | 5/5 |
| Arp | 5/5 | 5/5 |
| OspA (positive control) | 1/5 | 0/5 |
| P37-42 (negative control) | 5/5 | 5/5 |
a
Data are culture results of urinary bladder and inoculation site at 2 weeks after challenge with 104 B. burgdorferi cN40 cultured spirochetes or five B. burgdorferi cN40-infected ticks.