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. 2003 Dec;71(12):6820–6829. doi: 10.1128/IAI.71.12.6820-6829.2003

TABLE 1.

Cytokine concentrations in pleural wash fluids and sera from C57BL/6 (B6) and BALB/c (Bc) mice at D30 p.i.a

Sample Expta No. of mice (B6/Bc) Concn (pg/ml)b
IL-4
IL-5
IL-10
IFNγ
B6 Bc B6 Bc B6 Bc B6 Bc
Pleural wash fluidc 1 6/6 2.5 0.8 24.8 1.2 296.3 7.9 90.2 22.9
2 6/6 1.9 0 216.9 2 18,142.6 0 309.6 36.2
Serumd 2 6/6 0.1 0 159 28 18,290 0 4,084 0
3 8/8 8 0.2 102 36 15,165 525 2,660 265
4 6/3 2.95 0 347 4.7 5,412 130 5,253 844
a

Four experiments were performed, two for the pleural wash fluid and three for the serum; experiment 2 included both.

b

Concentrations, measured by two-site ELISA, in infected mice, values for naive mice were subtracted.

c

The combined results from the two experiments were statistically different (P < 0.01 for IL-4, IL-5, and IL-10 and P = 0.016 for IFN-γ) as calculated by the Mann-Whitney U test.

d

The combined results from the three experiments were statistically different (P < 0.0001 for IL-4, IL-5, and IFN-γ and P = 0.0002 for IL-10) as calculated by the Mann-Whitney U test.