FIG. 2.

(A and D) Disease pattern in CBA/H (circles), DBA/2 (squares), and (C57BL/6J × BALB/c)F₁ (triangles) mice infected intradermally in the ear (A) or tail (D) with 10⁴ L. major Friedlin metacyclic promastigotes. The mean lesion scores and standard deviations are shown as a function of time. (B and E) Parasite burden at 5, 10, and 15 weeks after infection with 10⁴ L. major Friedlin metacyclic promastigotes in the ear (B) or tail (E) are shown as in Fig. 1. (C and F) Ratio of IFN-γ to IL-4 at 0, 5, 10, and 15 weeks postinfection with 10⁴ L. major Friedlin metacyclic promastigotes in the ear (C) or tail (F) is shown as in Fig. 1.