TABLE 1.
Effect of MAb MG96 on P. yoelii development in An. stephensi mosquito midguts
| Treatment group | Dose (μg/ml) | % Reduction in infected midgutsa | No. of infected mosquitoes/number dissected (% infected) | P valueb |
|---|---|---|---|---|
| Control (no MAb) | 0 | 0 | 14/40 (35) | |
| Control MAb | 100 | 0 | 23/60 (38) | |
| MG96 | 10 | 74 | 2/20 (10) | 0.03 |
| 50 | 85 | 1/18 (6) | 0.04 | |
| 100 | 100 | 0/38 (0) | <0.01 |
a
Percent reduction in the number of infected midguts, i.e., 1 − (percent infected in treatment/percent infected in control with MAb) × 100. Results are from representative experiments from three trials.
b
Mann-Whitney U test, nonparametric analysis, α = 0.05.