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. Author manuscript; available in PMC: 2012 Apr 11.
Published in final edited form as: Toxicology. 2011 Jan 25;282(3):82–87. doi: 10.1016/j.tox.2011.01.013

Figure 4. TCDD-adsorbed silica dose response relationships.

Figure 4

Mice (N = 5) were treated with TCDD (6 µg/kg/day), silica (50 mg/kg/day), or TCDD-adsorbed silica for 5 days by oral gavage. (A.) 0–50 µg TCDD/kg/day loaded onto 50 mg silica/kg or (B.) 0–5 µg TCDD/kg/day loaded onto 50 mg silica/kg. On day 3, mice were sensitized with 5 × 108 sRBC per mouse i.p. Four days after sensitization, the number of anti-sRBC IgM AFC was determined from SPLC by plaque assay. *p<0.05 as compared to 0.