Table 2.
Adjusted Cumulative Odds Ratios of Adipose Depot Sizes and Their Association With the Severity of Fibrosis in Men, Premenopausal, and Postmenopausal Women
| Men | Premenopausal women | Postmenopausal women | ||||
|---|---|---|---|---|---|---|
| COR (95% CI) | P value | COR (95% CI) | P value | COR (95% CI) | P value | |
| Age, 10-y increase | 1.4 (1.0–1.8) | .021 | — | — | 1.7 (1.1–2.6) | .014 |
| Race, white | 2.3 (1.1–4.7) | .021 | — | — | — | — |
| Extremity size (EXT), 1 U increase | 0.7 (0.6–0.9) | .008 | 1.6 (1.2–2.2) | .003 | 1.0 (0.8–1.3) | .711 |
| Abdominal size (WAIST), 1 U increase | 0.8 (0.5–1.2) | .310 | 1.3 (0.7–2.5) | .357 | 1.6 (1.0–2.5) | .032 |
| Current smoking | — | — | — | — | ||
| Current alcohol use | 0.5 (0.3–0.8) | .008 | — | — | — | — |
| Total calorie intake, 500 Kcal/d increase | 0.9 (0.8–1.1) | .315 | 1.0 (0.8–1.3) | .955 | 0.9 (0.8–1.1) | .424 |
| Nonrecreational physical activities, 10 MET-h/wk increase | 1.0 (1.0–1.1) | .970 | 1.0 (0.9–1.0) | .820 | 1.0 (0.9–1.0) | .562 |
| Recreational physical activities, 10 MET-h/wk increase | 1.0 (1.0–1.0) | .375 | 0.9 (0.8–1.0) | .074 | 1.0 (0.9–1.0) | .861 |
| Sleep apnea | 1.5 (0.7–3.5) | .331 | 2.6 (0.6–10.6) | .181 | 1.4 (0.6–3.4) | .440 |
| Diabetes mellitus | 1.5 (0.8–2.8) | .169 | — | — | — | — |
| Hypertension | — | — | 2.1 (0.9–4.8) | .078 | — | — |
| Hypertriglyceridemia | — | — | 0.3 (0.1–0.7) | .009 | — | — |
| Low-HDL cholesterol | — | — | 1.5 (0.5–4.2) | .442 | — | — |
| High-LDL cholesterol | — | — | — | — | 0.7 (0.4–1.2) | .179 |
| Hyperuricemia | 0.2 (0.1–0.5) | <.001 | 1.8 (0.8–4.4) | .183 | — | — |
| Homa-IR, 5 U increase | — | — | 1.2 (0.7–2.2) | .555 | 1.4 (1.0–1.8) | .040 |
CI, confidence interval; COR, adjusted cumulative odds ratio; EXT, calculated parameter indicating extremity size; MET, metabolic equivalent of task; WAIST, standardized waist circumference (z-score).