Table 3a. Cumulative relationship between risk alleles with prostate cancer susceptibility amongst CaP patients with a “normal” PSA and DRE and healthy volunteer controls.

Cumulative risk model including all 17 risk alleles

Carrier of Variants #	Case N=203 N= (%)	Control N=611 N= (%)	OR (95%C.I.)	p-value
0-4	3 (1.5)	17 (2.8)	--
5	12 (5.9)	43 (7.0)	1.6 (0.4-6.3)	0.52
6	18 (8.9)	103 (16.9)	1.0 (0.3-3.7)	0.99
7	32 (15.8)	133 (21.8)	1.4 (0.4-4.9)	0.64
8	35 (17.2)	144 (23.6)	1.4 (0.4-5.0)	0.62
9	43 (21.2)	98 (16.0)	2.5 (0.7-8.9)	0.16
10	32 (15.8)	58 (9.5)	3.1 (0.9-11.5)	0.08
>10	28 (13.8)	15 (2.5)	10.6 (2.7-42.0)	0.0008

^*P-trend <0.001