Table 3a. Cumulative relationship between risk alleles with prostate cancer susceptibility amongst CaP patients with a “normal” PSA and DRE and healthy volunteer controls.
Carrier of Variants # |
Case N=203 N= (%) |
Control N=611 N= (%) |
OR (95%C.I.) |
p-value |
---|---|---|---|---|
0-4 | 3 (1.5) | 17 (2.8) | -- | |
5 | 12 (5.9) | 43 (7.0) | 1.6 (0.4-6.3) | 0.52 |
6 | 18 (8.9) | 103 (16.9) | 1.0 (0.3-3.7) | 0.99 |
7 | 32 (15.8) | 133 (21.8) | 1.4 (0.4-4.9) | 0.64 |
8 | 35 (17.2) | 144 (23.6) | 1.4 (0.4-5.0) | 0.62 |
9 | 43 (21.2) | 98 (16.0) | 2.5 (0.7-8.9) | 0.16 |
10 | 32 (15.8) | 58 (9.5) | 3.1 (0.9-11.5) | 0.08 |
>10 | 28 (13.8) | 15 (2.5) | 10.6 (2.7-42.0) | 0.0008 |
P-trend <0.001