Table 3c.

Cumulative risk model limited to the risk alleles that were significantly over-represented in CaP patients with a “normal” PSA and DRE (i.e. SNP rs2736098 along chromosome 5p15, SNP rs6983267 along 8q24, SNP rs1447295 along 8q24, SNP rs10993994 along 10q11, SNP rs11228565 along 11q13, rs1089649742 along 11q13)

Carrier of Variants #	Case N=203 N= (%)	Control N=611 N= (%)	OR (95%C.I.)	p-value
0	3 (1.5)	24 (3.9)	--
1	21 (10.3)	134 (21.9)	1.3 (0.3-4.5)	0.73
2	65 (32.0)	211 (34.5)	2.5 (0.7-8.4)	0.15
3	65 (32.0)	184 (30.1)	2.8 (0.8-9.7)	0.10
4-6	49 (24.1)	58 (9.5)	6.8 (1.9-23.8)	0.003

^*P-trend <0.001