Table 3d.

Cumulative risk model limited to the risk alleles that were significantly over-represented in CaP patients with a “normal” PSA and DRE and a positive family^*

Carrier of Variants #	Case N=195 N= (%)	Control N=348 N= (%)	OR (95%C.I.)	p-value
0	3 (1.5)	18 (5.2)	--
1	13 (6.7)	65 (18.7)	1.2 (0.3-4.6)	0.79
2	44 (22.6)	118 (33.9)	2.2 (0.6-8.0)	0.21
3	64 (32.8)	101 (29.0)	3.8 (1.1-13.4)	0.038
4-7	71 (36.4)	46 (13.2)	9.3 (2.6-33.2)	<0.0001

^*P-trend <0.001

^*Analyses were limited to cases (n=195) and controls (n=338) with available family history information