Figure 4.

Molecular structures showing the final frame of the MD simulations of the under-wound [65A⁽⁻¹⁾ and 65B⁽⁻¹⁾] and over-wound [65A⁽⁺¹⁾ and 65B⁽⁺¹⁾] 65 bp loops. Under-wound loops denature over multiple consecutive base pairs in two separate regions. Both over-wound loops develop one type II kink and another more severely denatured region which is similar to a type II kink but with additional broken base pairs.