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. 2011 Jan 19;39(9):3594–3606. doi: 10.1093/nar/gkq1342

Figure 3.

Figure 3.

Epigenetic pattern and CTCF binding at TSPY gene arrays. Four genes of the TSPY array have been shown with their repetitive histone modification and CTCF distribution patterns. The profile of H3K9me3 was used to divide the whole region in the domains of 20.7 kb (written in pink) and H3K9me3 demarcates each domain. One domain has been shown below separately, divided in four parts using colored lines (black, red, green and blue). The start site of the gene is sharply enriched with H3K9me3, which shows highest peak and then further decrease towards both the sides (∼6.4 kb). In the red-labeled (∼7.2 kb) region none of the tested antibodies show any enrichment whereas in the blue labeled (∼5.5 kb) region, there is little enrichment of H3K9me3 and CTCF. The black marked ∼1.6 kb region upstream of the gene also shows H3K9me3 and CTCF enrichment.