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Predicted secondary structure of the human HBII-180 box C/D snoRNAs. The characteristic features of members of the box C/D HBII-180 family are shown. Conserved C and D motifs are indicated by orange and cyan boxes/lines, respectively. The positions of rRNA complementary sequence are indicated by a green bar. The positions of M-box regions which can be altered to modulate target gene expression (snoMEN vector) (22) are indicated by a blue bar.
