Table 2.
Functional enrichment of genes related to T-DMRs identified only by QDMR based on biological process (BP)
| BP term | Gene number | Bonferroni P-value |
|---|---|---|
| Multicellular organismal process | 789 | 7.56E-15 |
| Homophilic cell adhesion | 59 | 4.80E-13 |
| Biological adhesion | 174 | 7.53E-10 |
| Cell–cell adhesion | 88 | 1.29E-09 |
| Cell adhesion | 173 | 1.33E-09 |
| Anatomical structure development | 485 | 2.25E-09 |
| Nervous system development | 243 | 2.27E-09 |
| System development | 449 | 1.38E-08 |
| Developmental process | 575 | 8.33E-08 |
| Multicellular organismal development | 527 | 2.78E-07 |
| System process | 299 | 5.24E-06 |
| Neurological system process | 249 | 7.04E-06 |
| Calcium-dependent cell–cell adhesion | 17 | 1.36E-05 |
| Cellular developmental process | 314 | 6.18E-03 |
| Cell differentiation | 303 | 6.22E-03 |
| Cell–cell signalling | 128 | 1.67E-02 |
| Anatomical structure morphogenesis | 228 | 2.12E-02 |
| Cell communication | 161 | 2.19E-02 |
| Synaptic transmission | 73 | 2.25E-02 |
| Cognition | 179 | 3.56E-02 |
| Neurogenesis | 126 | 4.85E-02 |
Only annotations with Bonferroni P < 0.05 for GO in all levels are listed here. Full lists and more details are provided in Supplementary Table S7.