Table 5.

Relative performance of the Karlin’s dinucleotide method versus its augmented version in detecting phylogenetically unique genes in S. enterica Typhi CT18 genome following the seven steps used in augmenting the method’s classification ability

Step	Method	Ambiguous	Native	Alien	TP	SN
1	Augmented	2315	1740	338	13	2.8
	Standard	–	–	–	–	–
2	Augmented	2208	1785	400	30	6.6
	Standard	–	3993	400	19	4.1
3	Augmented	2318	1789	286	30	6.6
	Standard	–	4106	287	7	1.5
4a	Augmented	1797	2242	354	52	11.4
	Standard	–	4038	355	14	3.0
4b	Augmented	1958	2041	394	68	15.0
	Standard	–	3999	394	18	3.9
4a and b	Augmented	1437	2494	462	90	19.8
	Standard	–	3930	463	31	6.8
5	Augmented	1437	2497	459	90	19.8
	Standard	–	3934	459	30	6.6
6	Augmented	1225	2497	671	158	34.8
	Standard	–	3722	671	62	13.6
7	Augmented	0	3281	1112	264	58.2
	Standard	–	3281	1112	120	26.4