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EGFP-apoE3 and EGFP-apoE4 localize to the ER and Golgi apparatus in Neuro-2a cells transiently transfected with RFP-ER. A–F, representative confocal images of EGFP-apoE (green) and RFP-ER (red) fluorescence in Neuro-2a cells expressing EGFP-apoE3 (A–C) or EGFP-apoE4 (D–F) are shown. The distinct morphology of the perinuclear Golgi apparatus with the strongest EGFP-apoE fluorescence is apparent.
