TABLE 2.
Genotype | TC | FC:TC | Hematocrit | Spleen |
---|---|---|---|---|
mg/dl | % | mg/g | ||
WT | 85 ± 17 | 26 ± 6 | 44.3 ± 3.2 | 4.3 ± 1.3 |
WT/CETP | 101 ± 23 | 24 ± 6 | 44.8 ± 1.7 | 4.6 ± 1.1 |
HypomSR-BI | 180 ± 20a | 27 ± 2 | 45.8 ± 2.9 | 3.8 ± 1.0 |
HypomSR-BI/CETP | 158 ± 15a | 27 ± 2 | 42.9 ± 3.8 | 4.6 ± 0.9 |
HypomSR-BI KOliver | 331 ± 56a | 62 ± 3a | 35.9 ± 6.2a | 22.0 ± 5.9a |
HypomSR-BI KOliver/CETP | 227 ± 48a,b | 61 ± 6a | 34.4 ± 3.9a | 21.3 ± 7.6a |
SR-BI−/− | 311 ± 43a | 62 ± 3a | 34.3 ± 3.9a | 25.8 ± 6.7a |
SR-BI−/−/CETP | 249 ± 28a,c | 62 ± 3a | 35.0 ± 4.1a | 22.2 ± 5.0a |
a p < 0.001, statistically different from values for control mice.
b p < 0.001, statistically different from values for corresponding non-CETP transgenic mice.
c p < 0.05, statistically different from values for corresponding non-CETP transgenic mice.