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. Author manuscript; available in PMC: 2011 May 6.
Published in final edited form as: Invest Ophthalmol Vis Sci. 2008 Dec 20;50(4):1739–1745. doi: 10.1167/iovs.08-2756

Figure 1.

Figure 1

Activation of NOD2 results in IFN-γ production within the eye. Mice were treated with intravitreal injection of 100 μg MDP or saline. IFN-γ production in whole eye tissue homogenates was measured by ELISA as a function of time after treatment (A) or in NOD2 knockout (NOD2 KO) compared with their control (wild-type [WT]) mice (B) 6 hours after treatment. Data are mean ± SEM. *P < 0.05 comparison between MDP and saline within a genotype. †P < 0.05 comparison between MDP-treated NOD2 KO and WT mice (n = 6–8 mice/treatment/time).