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. 2011 Apr 14;5(2):021501. doi: 10.1063/1.3574448

Figure 2.

Figure 2

An individual cell can traverse a microfluidic channel that contains an array of posts that are not aligned with the direction of flow along the channel. (a) Left: scheme of the motion of a cell that moves from one side of a microchannel to the other. A tracer stream is added to observe the direction of flow. Only objects above a certain size move across the channel. Right: SEM image of a microchannel that contains an array of posts that are not parallel with the walls of the microchannel. (c) The motion of an individual E. coli cell in a microchannel that contains an array of posts; the tracer stream in the channel is GFP. The cell contains GFP and, as it enters the region of the microfluidic channel that contains a solution that lyses cells, releases the GFP, which travels along the microchannel. Reprinted with permission from K. J. Morton et al., Lab Chip, 8, 1448 (2008). Copyright 2008 The Royal Society of Chemistry.