Table 3.
Adjusted and unadjusted total adrenal and thymus weights
| adjusted total adrenal (mg × 103/bw) |
adjusted thymus (mg × 103/bw) |
|||
|---|---|---|---|---|
| F344 (± SEM) |
F344/BN (± SEM) |
F344 (± SEM) |
F344/BN (± SEM) |
|
| 4 mo | 0.10 (± 0.00) |
0.11 (± 0.01) |
0.50** (± 0.05) |
0.62** † (± 0.03) |
| 12 mo | 0.10 (± 0.01) |
0.09 (± 0.00) |
0.18 (± 0.01) |
0.11 (± 0.02) |
| 24/30 mo | 0.14* (± 0.01) |
0.11* (± 0.01) |
0.18 (± 0.01) |
0.15 (± 0.02) |
| unadjusted total adrenal (mg × 103) |
unadjusted thymus (mg × 103) |
|||
|---|---|---|---|---|
| F344 (± SEM) |
F344/BN (± SEM) |
F344 (± SEM) |
F344/BN (± SEM) |
|
| 4 mo | 32.1 (± 2.0) |
38.7 (± 1.1) |
161.3 (± 18.0) |
211.9 (± 14.5) |
| 12 mo | 40.6 (± 3.5) |
45.0 (± 1.8) |
75.2 (± 6.3) |
57.0 (± 7.8) |
| 24/30 mo | 59.3 (± 5.0) |
63.3 (± 4.2) |
73.2 (± 6.5) |
82.1 (± 7.9) |
aged animals (combined across strain) had higher adrenal weights than middle aged
young animals (combined across strain) had higher thymus weights than both the middle aged and old groups
young F344/BN thymus weights were higher than young F344