. Author manuscript; available in PMC: 2012 Jun 16.

Published in final edited form as: J Am Chem Soc. 2010 Dec 16;133(2):379–386. doi: 10.1021/ja107424t

Table 1.

Hypothetical functions of proteins adjacent to the thiocarboxylate-forming protein, HcyS-Ala.

Protein IDs	Putative function of the proteins
WS1004, NP_907206 (sir)	Ferredoxin sulfite reductase^*
WS1005, NP_907207 (hcyD)	Metalloprotease involved in the removal of C-terminal alanine of HcyS-Ala prior to sulfur transfer and also in the release of homocysteine from HcyS-Homocysteine adduct^*
WS1006, NP_907208 (hcyF)	ATP-utilizing enzyme involved in adenylating HcyS C-terminal prior to sulfur transfer^*
WS1007, NP_907209 (hcyS-ala)	Sulfur transfer protein involved in methionine biosynthesis^*
WS1008 and WS1009, NP_907210 and NP_907211 (cysD and cysN)	Sulfate adenylyltransferase, subunits 1 and 2
WS1010, NP_907212 (cysH)	Phosphoadenylyl-sulfate reductase/Adenylyl-sulfate reductase
WS1011, NP_907213	Conserved hypothetical protein probably involved in assimilatory sulfate reduction
WS1012, NP_907214 (metY)	O-acetylhomoserine sulfhydrylase^*
WS1013, NP_907215	Methyltransferase (EC 2.1.1.-)
WS1014, NP_907216	Putative efflux protein
WS1015, NP_907217 (metZ)	O-acetylhomoserine or O-succinylhomoserine sulfhydrylase^*

Experimentally characterized in this study.