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. Author manuscript; available in PMC: 2012 May 1.
Published in final edited form as: Cancer Epidemiol Biomarkers Prev. 2011 Feb 25;20(5):779–792. doi: 10.1158/1055-9965.EPI-10-0845

Table 5.

Association between genotypes and risk of pancreatic cancer by BMI strataa

Genotype  BMI <25 kg/m2 BMI ≥25 kg/m2 
Case/control
(n/n)		 OR (95% CI) Case/control
(n/n)		 OR (95% CI)
ADIPOQ Ex3+117T>C
  TT 432/435 1.00 406/291 1.00
  CT 23/47 0.46 (0.26–0.79) 29/19 1.07 (0.57–2.01)
  CC 0/1 - - -
  CT/TT 23/48 0.45 (0.26–0.77) 29/19 1.07 (0.57–2.01)
FTO IVS1−27777C>A
  CC 183/164 1.00 136/127 1.00
  AC 207/241 0.69 (0.52–0.93) 222/133 1.73 (1.23–2.45)
  AA 70/75 0.74 (0.49–1.12) 78/49 1.61 (1.02–2.56)
  AC/AA 277/316 0.71 (0.53–0.93) 300/182 1.70 (1.23–2.35)
FTO IVS1−23525T>A
  TT 185/171 1.00 142/127 1.00
  AT 205/237 0.75 (0.56–1.01) 215/129 1.64 (1.17–2.32)
  AA 69/73 0.80 (0.53–1.20) 77/51 1.44 (0.91–2.27)
  AT/AA 274/310 0.76 (0.58–1.01) 292/180 1.59 (1.15–2.19)

AOR: adjusted odds ratio; 95% CI: 95% confidence interval; BMI: body mass index.

a

OR was adjusted for sex, age (continuous), race, education, smoking, alcohol, history of diabetes, and family history of cancer.