Table 5.
Multivariate adjusted rate ratios for colorectal adenomas according to aspirin use and two major dietary patterns
| Quintile | Cases | Person-years | Adjusted IRR (95% CI)1 | |
|---|---|---|---|---|
| Nonaspirin user | ||||
| Western | 1 | 88 | 24,841 | 1.00 |
| 2 | 100 | 25,034 | 1.16(0.87-1.55) | |
| 3 | 101 | 25,091 | 1.22(0.90-1.63) | |
| 4 | 91 | 24,849 | 1.14(0.84-1.54) | |
| 5 | 103 | 24,805 | 1.32(0.97-1.78) | |
| P, trend | 0.13 | |||
| Prudent | 1 | 104 | 25,944 | 1.00 |
| 2 | 96 | 25,370 | 0.89(0.67-1.19) | |
| 3 | 95 | 25,014 | 0.83(0.62-1.11) | |
| 4 | 99 | 24,343 | 0.83(0.62-1.11) | |
| 5 | 89 | 23,949 | 0.71(0.51-0.96) | |
| P, trend | 0.03 | |||
| | ||||
| Aspirin user | ||||
| Western | 1 | 24 | 5,893 | 1.00 |
| 2 | 20 | 5,647 | 0.97(0.52-1.77) | |
| 3 | 28 | 5,627 | 1.29(0.83-1.56) | |
| 4 | 27 | 5,812 | 1.17(0.82-2.58) | |
| 5 | 34 | 5,803 | 2.07(1.18-3.63) | |
| P, trend | < 0.01 | |||
| |
||||
| Prudent | 1 | 20 | 4,790 | 1.00 |
| 2 | 30 | 5,363 | 1.23(0.69-2.18) | |
| 3 | 27 | 5,616 | 0.95(0.52-1.73) | |
| 4 | 31 | 6,244 | 0.84(0.46-1.52) | |
| 5 | 25 | 6,768 | 0.61(0.32-1.15) | |
| P, trend | 0.04 | |||
1
Adjusted for age, BMI, education, family history of colorectal cancer, vigorous physical activity, total energy intake, menopausal status, alcohol consumption, smoking status and female hormone use.