Table 3 b.
Genetic Interactions of KIR and immunoglobulin allotypes in patients with HCV and HCV-DM.
| GM Allotypes and KIR genes | HCV-DM n=32 | HCV n=121 | p* (OR; CI) |
|---|---|---|---|
| n (%) | n (%) | ||
| 2DS4+ | 15 (47) | 50(41) | ns |
| 2DS4− | 17 (53) | 71(59) | ns |
| ff+ | 5 (16) | 21(17) | ns |
| ff− | 27 (84) | 100(83) | ns |
| KM3/KM3+ | 16 (50) | 56(46) | ns |
| KM3/KM3− | 16 (50) | 65(54) | ns |
| 2DS4(+) 2DL3/2DL3, 2DL1 | 8 (25) | 21(17) | ns |
| 2DS4(+) 2DL3/2DL3, 2DL1 ff+ | 3 (9) | 3(2) | ns |
| 2DS4(+) 2DL3/2DL3, 2DL1 ff− | 5 (16) | 18(15) | ns |
| 2DS4(+) 2DL3/2DL3, 2DL1 3/3+ | 2 (6) | 9(7) | ns |
| 2DS4(+) 2DL3/2DL3, 2DL1 3/3− | 6 (19) | 12(10) | ns |
| 2DS4(−) 2DL3/2DL3, 2DL1 | 13 (41) | 22(18) | 0.01 (3.07; 1.32–7.1) |
| 2DS4(−) 2DL3/2DL3, 2DL1 ff+ | 1 (3) | 5(4) | ns |
| 2DS4(−) 2DL3/2DL3, 2DL1 ff− | 12 (38) | 17(14) | 0.005 (3.67; 1.52–8.85) |
| 2DS4(−) 2DL3/2DL3, 2DL1 3/3+ | 9 (28) | 12(10) | 0.01 (3.55; 1.34–9.41) |
| 2DS4(−) 2DL3/2DL3, 3/3− | 4 (13) | 10(8) | ns |
HCV-DM: Hepatitis C infected patients with type 2 diabetes; HCV Non-DM: Hepatitis C infected patients without type 2 diabetes Haplotype A fragment: KIR 2DL3/2DL3, 2DL2 (−), 2DS1 (−), 2DS2 (−) 2DL1, 2DS4
p values analyzed by Fisher two tail exact method; OR= odds ratio; CI; confidence interval; ND: Not determined