Skip to main content
. Author manuscript; available in PMC: 2012 Jun 1.
Published in final edited form as: Immunobiology. 2010 Nov 5;216(6):686–691. doi: 10.1016/j.imbio.2010.10.006

Table 3 b.

Genetic Interactions of KIR and immunoglobulin allotypes in patients with HCV and HCV-DM.

GM Allotypes and KIR genes HCV-DM n=32 HCV n=121 p* (OR; CI)

n (%) n (%)
2DS4+ 15 (47) 50(41) ns
2DS4− 17 (53) 71(59) ns
ff+ 5 (16) 21(17) ns
ff− 27 (84) 100(83) ns
KM3/KM3+ 16 (50) 56(46) ns
KM3/KM3− 16 (50) 65(54) ns
2DS4(+) 2DL3/2DL3, 2DL1 8 (25) 21(17) ns
2DS4(+) 2DL3/2DL3, 2DL1 ff+ 3 (9) 3(2) ns
2DS4(+) 2DL3/2DL3, 2DL1 ff− 5 (16) 18(15) ns
2DS4(+) 2DL3/2DL3, 2DL1 3/3+ 2 (6) 9(7) ns
2DS4(+) 2DL3/2DL3, 2DL1 3/3− 6 (19) 12(10) ns
2DS4(−) 2DL3/2DL3, 2DL1 13 (41) 22(18) 0.01 (3.07; 1.32–7.1)
2DS4(−) 2DL3/2DL3, 2DL1 ff+ 1 (3) 5(4) ns
2DS4(−) 2DL3/2DL3, 2DL1 ff− 12 (38) 17(14) 0.005 (3.67; 1.52–8.85)
2DS4(−) 2DL3/2DL3, 2DL1 3/3+ 9 (28) 12(10) 0.01 (3.55; 1.34–9.41)
2DS4(−) 2DL3/2DL3, 3/3− 4 (13) 10(8) ns

HCV-DM: Hepatitis C infected patients with type 2 diabetes; HCV Non-DM: Hepatitis C infected patients without type 2 diabetes Haplotype A fragment: KIR 2DL3/2DL3, 2DL2 (−), 2DS1 (−), 2DS2 (−) 2DL1, 2DS4

p*

p values analyzed by Fisher two tail exact method; OR= odds ratio; CI; confidence interval; ND: Not determined