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. Author manuscript; available in PMC: 2012 Jun 1.

Published in final edited form as: Immunobiology. 2010 Nov 5;216(6):686–691. doi: 10.1016/j.imbio.2010.10.006

Table 4.

Genetic Interactions between HLA C group and 2DL1 in patients with HCV, HCV-DM and DM.

	A	B	C

	DM n (%)	HCV-DM n (%)	HCV n (%)	^p* (OR)	^p# (OR)
C1/C1	33 (35.5)	10 (34.5)	41 (33.9)	(1.05)	(1.03)
C1/C2	40 (43.0)	16 (55.2)	50 (41.3)	(0.61)	(1.82)
C2/C2	20 (21.5)	6 (20.7)	30 (24.8)	(1.06)	(0.75)
KIR 2DL3/2DL3, 2DS4 (−), 2DL1	10 (10.7)	11 (37.9)	22 (17.7)	0.001 (5.07)	0.020 (2.83)
KIR 2DL3/2DL3, 2DS4 (−), 2DL1	6 (6.4)	2 (6.9)	7 (5.6)	(1.07)	(1.23)
C1/C1
KIR 2DL3/2DL3, 2DS4 (−), 2DL1	4 (4.3)	7 (24.1)	10 (8.1)	0.004 (7.07)	0.018 (3.62)
C1/C2
KIR 2DL3/2DL3, 2DS4 (−), 2DL1	0	2 (6.9)	5 (4.0)	(0.15)	(1.76)
C2/C2
KIR 2DL3/2DL3, 2DS4 (−), 2DL1	10 (10.7)	9 (31.0)	17 (13.7)	0.012 (3.73)	0.03 (2.83)
C1 one or two copies
KIR 2DL3/2DL3, 2DS4 (−), 2DL1	4 (4.3)	9 (31.0)	15 (12.1)	<0.0001 (10.0)	0.015 (3.27)
C2 one or two copies

C1: HLA-C Group 1; C2: HLA-C p: p values analyzed by logistic regression analysis; OR; odds ratio.

^p*

p value calculated between columns A and B

^p#

p value calculated between columns B and C. p values were calculated by Fisher two tail exact method.