Table 5.

Equivalent Cutoffs by Assay

		Corresponding Cutoffs*
Class I (Class I only or Class I and II)	One Lambda LABScreen Mixed NBG cutoff	2.2a	10.0 b	12.0 c	14.0 d	22.9 c	30.0 b	59.3 b
	GTI QuickStep cutoff	0.4	0.6	0.7	0.7	1.0	1.2	2.1
	One Lambda LATM20	5.3	8.9	9.8	10.7	14.8	18.1	31.5
	Tepnel Lifescreen	−0.3	3.6	4.7	5.7	10.2	13.8	28.8
	3Ti Aegis	3.1	6.2	7.0	7.8	11.4	14.2	25.9
	% of Ever Pregnant Females Positive for HLA Ab	44.7% e	19.8% e	19.5% e	17.5% e	15.2% e	12.5% e	7.4% e
Class II (Class II only or Class I and II)	One Lambda LABScreen Mixed NBG cutoff	2.2a	9.0 c, d	10.0 b	15.0 b	16 c	27.5 b
	GTI QuickStep cutoff	0.4	0.5	0.6	0.7	0.7	0.9
	One Lambda LATM20	5.3	9.2	9.8	12.6	13.2	19.7
	Tepnel Lifescreen	0.4	4.4	5.0	8.0	8.6	15.4
	3Ti Aegis	3.4	6.6	7.1	9.5	10.0	15.5
	% of Ever Pregnant Females Positive for HLA Ab	28.0% e	16.3% e	16.3% e	14.4% e	14.4% e	11.3% e

^*The data presented show cutoffs that are roughly equivalent to each other in terms of positivity rates in ever pregnant donors. The data is organized based on increasing One Lambda LABScreen Mixed NBG cutoff values that are currently in use by laboratories across the U.S.

^aManufacturer’s suggested cutoff for organ transplantation;

^bReported cutoff used by blood bank laboratories ²¹;

^cCutoff used by Vassallo et al. ²⁵;

^dREDS-II LAPS serum adjusted cutoff ¹⁷,²⁹;

^ePercent positive may differ from that reported in Table 2 as calculations are based on the latent variable score and not observed values.