Table 5.
Energy-Adjusted Dietary Intakes and Risk of Endometrial Cancer Stratified by Menopausal Status, NHS Cohort (1980–2006)
| Premenopausal* |
Postmenopausal† |
Pheterogeneity | |||||||
|---|---|---|---|---|---|---|---|---|---|
| # of Cases | Median | RR | 95% CI | # of Cases | Median | RR | 95% CI | ||
| Total Energy | |||||||||
| Q1 | 19 | 1069 | 1.00 | 84 | 1158 | 1.00 | 0.93 | ||
| Q2 | 7 | 1372 | 0.40 | 0.17, 0.95 | 126 | 1447 | 1.51 | 1.14, 1.99 | |
| Q3 | 18 | 1602 | 0.98 | 0.51, 1.87 | 114 | 1660 | 1.37 | 1.04, 1.82 | |
| Q4 | 21 | 1854 | 1.09 | 0.58, 2.04 | 124 | 1896 | 1.51 | 1.14, 1.99 | |
| Q5 | 28 | 2267 | 1.42 | 0.77, 2.57 | 97 | 2276 | 1.19 | 0.89, 1.60 | |
| Ptrend | 0.09 | 0.12 | |||||||
| Animal Fat | |||||||||
| Q1 | 20 | 30.8 | 1.00 | 107 | 26.9 | 1.00 | 0.0008 | ||
| Q2 | 24 | 38.0 | 1.04 | 0.57, 1.89 | 115 | 32.7 | 1.09 | 0.84, 1.42 | |
| Q3 | 24 | 43.5 | 0.92 | 0.50, 1.67 | 122 | 36.9 | 1.14 | 0.87, 1.48 | |
| Q4 | 14 | 48.0 | 0.51 | 0.26, 1.02 | 104 | 41.0 | 0.98 | 0.75, 1.29 | |
| Q5 | 11 | 60.4 | 0.36 | 0.17, 0.76 | 97 | 49.4 | 0.95 | 0.71, 1.25 | |
| Ptrend | 0.0009 | 0.80 | |||||||
| Carbohydrates | |||||||||
| Q1 | 10 | 125 | 1.00 | 81 | 148 | 1.00 | 0.94 | ||
| Q2 | 15 | 156 | 1.49 | 0.67, 3.32 | 112 | 172 | 1.20 | 0.91, 1.59 | |
| Q3 | 26 | 171 | 2.72 | 1.30, 5.68 | 125 | 186 | 1.35 | 1.03, 1.78 | |
| Q4 | 19 | 184 | 2.07 | 0.96, 4.48 | 103 | 198 | 1.10 | 0.83, 1.47 | |
| Q5 | 23 | 207 | 2.87 | 1.35, 6.08 | 117 | 218 | 1.23 | 0.92, 1.63 | |
| Ptrend | 0.004 | 0.27 | |||||||
| Cereal fiber | |||||||||
| Q1 | 17 | 1.35 | 1.00 | 76 | 2.12 | 1.00 | 0.05 | ||
| Q2 | 25 | 2.35 | 1.54 | 0.82, 2.87 | 104 | 3.11 | 1.26 | 0.94, 1.70 | |
| Q3 | 21 | 2.95 | 1.27 | 0.66, 2.43 | 121 | 3.83 | 1.41 | 1.06, 1.89 | |
| Q4 | 17 | 3.70 | 1.17 | 0.59, 2.32 | 109 | 4.67 | 1.24 | 0.92, 1.66 | |
| Q5 | 13 | 5.20 | 1.09 | 0.52, 2.29 | 135 | 6.30 | 1.48 | 1.11, 1.97 | |
| Ptrend | 0.88 | 0.02 | |||||||
Adjust for total energy (continuous), smoking [never(reference), past, current], oral contraceptive use [never (reference), < 3 years, 3, 5 years, > 5 years], parity [nulliparous (reference), 1, 2 & age at last birth<30, 1, 2 & age at last birth>=30, 3, 4 & age at last birth<30, 3, 4 & age at last birth>=30, 5+], age at menarche [< 12, 12 (reference), > 12], hypertension (yes, no), diabetes (yes, no), BMI (continuous).
Adjust for total energy (continuous), smoking [never(reference), past, current], oral contraceptive use [never (reference), < 3 years, 3, 5 years, > 5 years], postmenopausal hormone use [postmenopausal never(reference), past, current E only, current E+P], age at menopause [pre/unknown menopause, <45 yr, 45, 46 yr, 47, 48 yr (reference), 49, 50 yr, 51, 52 yr, 53+ yr], parity [nulliparous (reference), 1, 2 & age at last birth<30, 1, 2 & age at last birth>=30, 3, 4 & age at last birth<30, 3, 4 & age at last birth>=30, 5+], age at menarche [< 12, 12 (reference), > 12], hypertension (yes, no), diabetes (yes, no), BMI (continuous).