Table 5.

Multivariate logistic regression analysis for the association between PSC lens opacity and donor status.

Model number	Covariates included in model	Reference group	Odds ratio*	Lower 95% CI	Upper 95% CI	P
1	Age	Per year	1.115	1.035	1.201	0.004
	Donor type	Platelet†	2.822	0.829	9.608	0.097
2	Age	Per year	1.119	1.038	1.206	0.003
	Donor type	Platelet	2.870	0.837	9.840	0.094
	Alcohol intake	< 1.5 oz per day	0.364	0.042	3.113	0.356
3	Age	Per year	1.116	1.035	1.203	0.004
	Donor type	Platelet	2.887	0.838	9.942	0.093
	Body mass index	<26	0.438	0.135	1.420	0.169
4	Age	Per year	1.117	1.037	1.203	0.004
	Donor type	Platelet	2.855	0.830	9.827	0.096
	Ocular risk factor index ‡	None	2.464	0.674	9.008	0.173
5	Age	Per year	1.121	1.039	1.209	0.003
	Donor type	Platelet	3.096	0.893	10.734	0.075
	Sex	Male	1.917	0.590	6.234	0.279

^*Adjusted for all other covariates in the model. An odds ratio >1 indicates that the potential risk factor (versus the reference category) has a higher risk of PSC lens opacity. For example, after adjusting for age, granulocyte donors have a higher risk of PSC lens opacity, compared with platelet donors (odds ratio = 2.822, i.e., 282.2% higher in granulocyte donors than in platelet donors), but this risk does not achieve statistical significance (p=0.097).

^†Number of granulocyte donations <4.

^‡Any history of glaucoma, uveitis, ocular trauma, or ocular surgery (glaucoma surgery or retinal detachment repair).