Table 1.
Characteristics of GBM-derived cultures presenting EGFR overdosage
| GBM | Adherent culture lengtha | Spherical aggregates | EGFR status | EGFRvIII |
|---|---|---|---|---|
| G1 | Short-term (p0–p10) | Yes | Amplification | No |
| G16 | Long-term (p0–p50) | No | Polysomy 7 and EGFR locus | No |
| G32 | Short-term (p0–p5) | Yes | Amplification | No |
| G33 | Long-term (p0–p25) | No | Polysomy 7 and EGFR locus | No |
| G48 | Short-term (p0–p10) | Yes | Amplification | Yes |
| G54 | Passage 0 only | No | Non verified | No |
aShort-term culture (up to 8–12 weeks at most); long-term culture (up to 20–24 weeks at most)