Table 3.
Analysis of selected articles
Alonso et al. [25] | Dickinson et al. [26] | Herford et al. [27] | |
---|---|---|---|
Total number of patients | 16 | 21 | 12 |
rhBMP-2 group | 8 | 9 | 10 |
Type of alveolar cleft | Unilateral only | Unilateral only | Unilateral only |
Timing of intervention | Mixed dentition | Skeletally mature | Mixed dentition |
Carrier used for rhBMP-2 | Absorbable collagen sponge | Absorbable collagen sponge | Absorbable collagen sponge |
Control group graft | Particulate iliac crest cancellous bone | Particulate iliac crest cancellous bone | Particulate iliac crest cancellous bone |
Method for measuring outcome | CT, coronal CT slices | CTa, 3D CT reconstructionsa, OPG, periapical films | CT |
Follow-up | 12 months | 12 months | 4 months |
Type of study | Randomised controlled trial | Randomised controlled trial | Retrospective controlled review |
aAlthough follow-up was 12 months, CT scans were performed at 6 months postoperatively by Dickinson et al. [26]