Table 5.

Complications and adverse events

	Alonso et al. [25]	Dickinson et al. [26]	Herford et al. [27]
rhBMP-2 group	37.5% local postoperative swelling	1 patient, prolonged healing	Postoperative swelling
			2 patients with less than 25% bone formation
Control group	87.5% donor site pain	5 patients, partial loss of graft
		1 patient, near complete loss of graft
		3 patients, persistent oronasal fistula at 6 weeks postoperative donor site pain