Table II.
Diabetes Effect on Cardiovascular Risk Factors from Multiple Regression Models, Adjusted for Age, Sex, and Ethnicity
| Cardiovascular Risk Factors | With T1D (n=29) | Without T1D (n=37) | P Value |
|---|---|---|---|
| Body composition | |||
| Waist circumference, cma | |||
| Normal weight | 71.7±1.8 | 70.0±1.7 | .2347 |
| Overweight | 93.4±4.9 | 99.3±3.0 | .2684 |
| Waist to hip ratio, cm | 0.79±0.02 | 0.79±0.01 | .9747 |
| Body fat, %a | |||
| Normal weight | 24.3±1.7 | 21.4±1.6 | .1814 |
| Overweight | 36.7±2.7 | 36.5±1.7 | .1896 |
| Total fat mass, kga | |||
| Normal weight | 13.4±1.1 | 11.3±1.1 | .1619 |
| Overweight | 29.9±4.2 | 36.2±2.6 | .1751 |
| Fat‐free mass, kg | 48.5±2.0 | 50.5±1.5 | .3860 |
| Trunk fat mass, kga | |||
| Normal weight | 4.7±0.6 | 4.4±0.6 | .6673 |
| Overweight | 12.9±2.3 | 17.0±1.4 | .0991 |
| Lipid profile | |||
| Triglycerides, mg/dL | 79.9±9.9 | 89.6±7.2 | .3826 |
| Cholesterol, mg/dL | 165.9±8.4 | 151.5±6.1 | .1310 |
| HDL‐C, mg/dL | 46.6±2.5 | 37.5±1.8 | .0023b |
| LDL‐C, mg/dL | 103.3±7.4 | 96.0±5.4 | .3863 |
| LDL‐C:HDL‐C ratio | 2.3±0.2 | 2.7±0.2 | .1311 |
| Apolipoprotein | |||
| ApoB | 75.0±3.1 | 69.9±2.2 | .1422 |
| ApoC‐III | 6.7±0.5 | 6.6±0.4 | .8854 |
| ApoC‐III HS | 4.2±0.3 | 3.8±0.2 | .3292 |
| ApoC‐III HP | 2.4±0.3 | 2.5±0.2 | .7185 |
| Vascular measures | |||
| Mean arterial pressure, mm Hg | 82.3±2.0 | 79.2±1.4 | .1755 |
| Systolic BP, mm Hg | 116.6±2.4 | 115.4±1.7 | .6690 |
| Diastolic BP, mm Hg | 62.9±1.7 | 59.3±1.2 | .0619 |
| Large artery elasticity index | 16.9±1.3 | 17.1±0.9 | .8788 |
| Small artery elasticity index | 8.4±0.6 | 9.4±0.4 | .1331 |
Values are expressed as least squares means±standard error. Abbreviations: BP, blood pressure; ApoB, apolipoprotein B; ApoC‐III HP, apolipoprotein C‐III heparin precipitate (see Methods); ApoC‐III HS, apolipoprotein C‐III heparin supernate; HDL‐C, high‐density lipoprotein cholesterol; LDL‐C, low‐density lipoprotein cholesterol; N/A, not applicable; T1D, type 1 diabetes. aStatistically significant interaction between diabetes status and weight status is present in the model, therefore the model is stratified by weight status. bStatistically significant difference.