Table III.
Weight Effect on Cardiovascular Risk Factors from Multiple Regression Models, Adjusted for Age, Sex, and Ethnicity
| Cardiovascular Risk Factors | Normal Weight (n=28) | Overweight (n=38) | P Value |
|---|---|---|---|
| Body composition | |||
| Waist circumference, cma | N/A | N/A | N/A |
| Waist to hip ratio, cm | 0.75±0.01 | 0.82±0.01 | .0001b |
| Body fat, %a | N/A | N/A | N/A |
| Total fat mass, kga | N/A | N/A | N/A |
| Fat‐free mass, kg | 43.1±1.8 | 55.9±1.6 | <.0001b |
| Trunk fat mass, kga | N/A | N/A | N/A |
| Lipid profile | |||
| Triglycerides, mg/dL | 77.1±8.8 | 92.4±8.1 | .1518 |
| Cholesterol, mg/dL | 156.7±7.4 | 160.6±6.9 | .6625 |
| HDL‐C, mg/dL | 42.9±2.2 | 41.2±2.1 | .5320 |
| LDL‐C, mg/dL | 98.4±6.6 | 100.9±6.1 | .7519 |
| LDL‐C:HDL‐C ratio | 2.4±0.2 | 2.6±0.2 | .5192 |
| Apolipoprotein | |||
| ApoB | 69.7±2.8 | 75.2±2.5 | .1005 |
| ApoC‐III | 6.1±0.4 | 7.1±0.1 | .0782 |
| ApoC‐III HS | 3.9±0.3 | 4.1±0.3 | .6618 |
| ApoC‐III HP | 2.1±0.3 | 2.7±0.3 | .0826 |
| Vascular measures | |||
| Mean arterial pressure, mm Hg | 79.5±1.8 | 82.0±1.6 | .2476 |
| Systolic BP, mm Hg | 114.7±2.2 | 117.4±2.0 | .2914 |
| Diastolic BP, mm Hg | 60.7±1.5 | 61.4±1.4 | .6852 |
| Large artery elasticity index | 16.3±1.1 | 17.7±1.0 | .3056 |
| Small artery elasticity index | 7.8±0.5 | 10.0±0.5 | .0007b |
Values are expressed in least squares means±standard error. Abbreviations: BP, blood pressure; ApoB, apolipoprotein B; ApoC‐III HP, apolipoprotein C‐III heparin precipitate (see Methods); ApoC‐III HS, apolipoprotein C‐III heparin supernate; HDL‐C, high‐density lipoprotein cholesterol; LDL‐C, low‐density lipoprotein cholesterol; N/A, not applicable. aStatistically significant interaction between diabetes status and weight status is present in the model. Stratified model is presented in diabetes effect table. bStatistically significant difference.