Table V.
Weight Effect on Cardiovascular Risk Factors from Multiple Regression Models in T1D Patients, Adjusted for Age, Sex, and Ethnicity
| Cardiovascular Risk Factors | Normal Weight (n=14) | Overweight (n=15) | P Value |
|---|---|---|---|
| Body composition | |||
| Waist circumference, cm | 74.1±3.9 | 91.5±4.6 | .0002a |
| Waist to hip ratio, cm | 0.8±0.03 | 0.8±0.03 | .0809 |
| Body fat, % | 25.5±2.2 | 36.2±2.6 | <.0001a |
| Total fat mass, kg | 14.6±2.7 | 28.3±3.2 | <.0001a |
| Fat‐free mass, kg | 40.9±3.7 | 50.6±4.3 | .0138a |
| Trunk fat mass, kg | 5.6±1.4 | 12.3±1.7 | <.0001a |
| Lipid profile | |||
| Triglycerides, mg/dL | 78.0±16.2 | 111.2±19.4 | .0541 |
| Cholesterol, mg/dL | 173.4±11.4 | 176.9±13.6 | .7610 |
| HDL‐C, mg/dL | 47.4±4.5 | 47.2±5.4 | .9565 |
| LDL‐C, mg/dL | 110.4±9.5 | 107.4±11.4 | .7590 |
| LDL‐C:HDL‐C ratio | 2.4±0.3 | 2.3±0.4 | .8743 |
| Apolipoprotein | |||
| ApoB | 74.1±4.6 | 79.8±5.5 | .2367 |
| ApoC‐III | 7.1±0.9 | 9.0±1.1 | .0453a |
| ApoC‐III HS | 4.6±0.6 | 5.3±0.8 | .2744 |
| ApoC‐III HP | 2.4±0.5 | 3.3±0.6 | .0761 |
| Vascular measures | |||
| Mean arterial pressure, mm Hg | 83.7±3.2 | 83.2±3.8 | .8834 |
| Systolic BP, mm Hg | 117.7±3.5 | 119.2±4.2 | .6851 |
| Diastolic BP, mm Hg | 62.5±3.0 | 61.1±3.7 | .6626 |
| Large artery elasticity index | 16.7±1.5 | 19.9±1.8 | .0507 |
| Small artery elasticity index | 7.8±1.0 | 9.7±1.2 | .0645 |
Values are expressed as least squares means±standard error. Abbreviations: ApoB, apolipoprotein B; BP, blood pressure; ApoC‐III HP, apolipoprotein C‐III heparin precipitate (see Methods); ApoC‐III HS, apolipoprotein C‐III heparin supernate; N/A, not applicable. aStatistically significant difference.