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. Author manuscript; available in PMC: 2011 May 7.
Published in final edited form as: J Pharm Sci. 2010 Mar;99(3):1180–1192. doi: 10.1002/jps.21928

Table 2. Observed Entrapment Parameters for the 12 Formulations of PB Design.

Formulation Number Percentage Theoretical Drug Loading Percentage Actual Drug Loading Percentage Actual PLGA Loading Entrapment Efficiency
1 20 17.3 ± 0.02 82.7 86.62 ± 0.09
2 20 2.1 ± 0.01 97.9 10.31 ± 0.04
3 20 2.2 ± 0.00 97.8 11.17 ± 0.00
4 11.1 5.5 ± 0.00 94.5 49.26 ± 0.02
5 11.1 7.3 ± 0.01 92.7 65.74 ± 0.13
6 11.1 2.6 ± 0.00 97.4 23.25 ± 0.04
7 33.3 31.0 ± 0.03 69.0 93.07 ± 0.08
8 33.3 29.2 ± 0.02 70.8 87.68 ± 0.05
9 33.3 10.8 ± 0.00 89.2 32.35 ± 0.01
10 20 17.5 ± 0.01 82.5 87.44 ± 0.03
11 20 4.6 ± 0.01 95.4 23.22 ± 0.06
12 20 2.0 ± 0.01 98.0 10.62 ± 0.06