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. Author manuscript; available in PMC: 2012 May 1.
Published in final edited form as: Hypertension. 2011 Apr 4;57(5):1010–1017. doi: 10.1161/HYPERTENSIONAHA.110.168906

Figure 5. Inhibition of AMPK elevates the p190-GAP dependent RhoA activation in vivo.

Figure 5

Aortic tissue from WT, AMPKα1−/−, and AMPKα2−/− mice was subjected to coimmunoprecipitation/western blot to analyze (A) serine phosphorylation of p190-GAP, (B) p190-GAP/RhoA binding, and (C) rhotekin pull-down assays to determine levels of active RhoA. n=6, *P<0.05 vs. WT.