Table 2.
Levels of eight hormones related to energy homeostasis, and BMI in 21 subjects, according to H. pylori eradication status
| Median (IQR) hormone concentration (pg/ml), before and after H. pylori eradication | Comparison of values at baseline and after eradication (p-value) |
|||||||
|---|---|---|---|---|---|---|---|---|
| Baseline | Eradicated | |||||||
| Hormone | Pre-meal | Post-meal | pb | Pre-meal | Post-meal | pb | Pre-meal | Post-meal |
| Amylin | 15 | 19 | 0.046 | 16 | 36 | 0.008 | 0.25 | 0.16 |
| (14-43) | (15-54) | (15-50) | (15-106) | |||||
| Insulin | 243 | 584 | < 0.001 | 265 | 763 | < 0.001 | 0.39 | 0.28 |
| (129-414) | (462-1,475) | (139-558) | (430-2,100) | |||||
| Ghrelin | 1,024 | 231 | 0.004 | 1,710 | 1,586 | 0.12 | 0.51 | 0.005 |
| (7-3,461) | (7-1,329) | (27-4,573) | (13-3,360) | |||||
| GIP | 15 | 107 | 0.001 | 27 | 82 | 0.001 | 0.82 | 0.85 |
| (5-29) | (29-214) | (9-54) | (41-282) | |||||
| GLP-1 | 28 | 16 | 0.51 | 36 | 45 | 0.95 | 0.11 | 0.04 |
| (10-56) | (9-59) | (12-89) | (14-91) | |||||
| Leptin | 4,260 | 5,690 | 0.02 | 6,605 | 7,400 | 0.02 | 0.001 | < 0.001 |
| (1,890-6,649) | (1,765-11,350) | (3,517-14,600) | (4,120-17,925) | |||||
| PP | 63 | 107 | 0.005 | 79 | 112 | 0.001 | 0.31 | 0.23 |
| (18-113) | (44-204) | (26-153) | (45-172) | |||||
| PYY | 39 | 70 | 0.002 | 61 | 70 | 0.001 | 0.02 | 0.34 |
| (27-82) | (48-98) | (34-90) | (47-137) | |||||
a p-values < 0.05 are indicated in bold
b Wilcoxon's signed rank test comparing pre-meal and post-meal values.
c Paired t-test comparing BMI at baseline to after H. pylori eradication.