Table 2.
Performance of non-invasive markers for prediction of esophageal/gastric varices
| Splenomegaly | APRI | Fibroscan | |
|---|---|---|---|
| Cut-off | - | 1.92 | 12.7 |
| Sensitivity (%) | 92 | 84 | 84 |
| Specificity (%) | 85 | 83 | 77 |
| PPV (%) | 88 | 85 | 81 |
| NPV (%) | 91 | 83 | 81 |
| Accuracy (%) | 89 | 84 | 83 |
| LR+ | 6.15 | 5.08 | 4.23 |
| LR- | 0.09 | 0.18 | 0.19 |
| AUC | - | 0.87 | 0.89 |
| 95% CI | 0.85-0.99 | 0.78-0.96 | 0.80-0.98 |
APRI, AST-to-platelet ratio index; PPV, positive predictive value; NPV, negative predictive value; LR+, likelihood ratio for positive results; LR-, likelihood ratio for negative results; AUC, area under the curve; CI, confidence interval.