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. 2011 Apr 15;12:193. doi: 10.1186/1471-2164-12-193

Table 5.

Functional enrichment analysis of differentially regulateda genes elicited by TCDD in Hepa1c1c7 cells using DAVID.

Category Term Gene count Fold enrichment P-value
Enrichment Score: 18.67
 GOTERM_BP_3 GO:0000278 ~ mitotic cell cycle 43 5.95 7.67E-21
 GOTERM_BP_3 GO:0022402 ~ cell cycle process 52 4.50 1.15E-19
 GOTERM_BP_3 GO:0022403 ~ cell cycle phase 47 4.87 3.67E-19
 GOTERM_BP_3 GO:0048285 ~ organelle fission 36 6.14 6.31E-18
Enrichment Score: 2.05
 GOTERM_BP_3 GO:0006805 ~ xenobiotic metabolic process 4 11.20 4.67E-03
 GOTERM_BP_3 GO:0009410 ~ response to xenobiotic stimulus 4 8.96 9.05E-03
 GOTERM_BP_3 GO:0006725 ~ cellular aromatic compound metabolic process 9 2.75 1.66E-02
Enrichment Score: 2.04
 GOTERM_BP_3 GO:0048522 ~ positive regulation of cellular process 58 1.51 1.41E-03
 GOTERM_BP_3 GO:0042127 ~ regulation of cell proliferation 27 1.72 7.62E-03
 GOTERM_BP_3 GO:0008284 ~ positive regulation of cell proliferation 14 1.69 7.12E-02
Enrichment Score: 1.62
 GOTERM_BP_3 GO:0051640 ~ organelle localization 7 4.36 5.10E-03
 GOTERM_BP_3 GO:0051651 ~ maintenance of location in cell 4 5.38 3.68E-02
 GOTERM_BP_3 GO:0051235 ~ maintenance of location 4 4.07 7.35E-02

aDifferentially regulated genes with P1(t) > 0.999 and |foldchange| > 1.4