Fig. 3.

MR spectral differences in patients with SCA2, SCA6, and MSA-C relative to controls. Localized proton MR spectra (STEAM, TE=5 ms, TR=4.5 s, 128 transients) obtained from the vermis, cerebellar hemisphere, and pons are shown. All spectra were processed identically and weighted with the same Gaussian function prior to Fourier transformation. Visible metabolite alterations are shown with arrows that indicate the direction of change. tNAA total N-acetylaspartate, Glu glutamate, Gln glutamine, myo-Ins myo-inositol, tCr total creatine, tCho total choline, Lac lactate, Glc glucose, Tau taurine