Figure 4.
Gli1(+) cells in the telogen hair follicle are multipotent.
(A) Whole mount X-gal staining in anagen follicles isolated from Gli1-GIFM skin induced at clonal frequency during telogen. Examples of labeling in multiple epithelial lineages, a single lineage (HS), bulge only, and in the DP. Arrowhead; labeling in bulge region. Scale bar=100μm.
(B) Frequency of anagen follicles with labeling after clonal Gli1-GIFM during telogen. follicle clones; any epithelial lineage.
(C) Frequency of staining in epithelial lineage compartments among labeled follicles. single; restricted to one lineage compartment, multiple (multi); at least two lineages.