Skip to main content
. Author manuscript; available in PMC: 2011 May 9.
Published in final edited form as: Bioorg Med Chem Lett. 2009 Nov 13;20(1):60–64. doi: 10.1016/j.bmcl.2009.11.031

Scheme 1.

Scheme 1

Reagents and conditions: (a) TMSCl, (i-BuCO)2O, pyridine, rt, 4 h, 75%; (b) Bz2O, DMF, Et3N, rt 2 h, 74%; (c) (i) Tf2O, DCM, pyridine, 0 °C, (ii) H2O, (iii) MeOH, NaHCO3; 32%; (d) (i) MsCl, DCM, DMAP, 0 °C, 40 min, (ii) NaN3, DMF, 120 °C, 2 h, 65%, two steps; (e) NaOCH3/MeOH, DCM 45 °C, 4 h, 82%.