Table 2.
Back-calculated concentrations of alfentanil calibration standards in human plasma
| Nominal Concentration (ng/ml) | Calculated Concentration (ng/ml)
|
Mean | SD | %CV | %Difference | |||||
|---|---|---|---|---|---|---|---|---|---|---|
| Run 1 | Run 3 | Run 3 | ||||||||
| 0.25 | 0.24 | 0.26 | 0.25 | 0.25 | 0.23 | 0.26 | 0.25 | 0.01 | 4.8 | 0.6 |
| 0.5 | 0.54 | 0.48 | 0.50 | 0.52 | 0.44 | 0.49 | 0.50 | 0.03 | 6.8 | 1.1 |
| 1 | 1.17 | 1.00 | 1.07 | 0.93 | 0.90 | 1.02 | 1.02 | 0.10 | 9.5 | -1.6 |
| 2.5 | 2.43 | 2.56 | 2.58 | 2.87 | 2.27 | 2.45 | 2.53 | 0.20 | 8.0 | -1.1 |
| 5 | 4.90 | 4.74 | 5.25 | 5.32 | 5.36 | 5.14 | 5.12 | 0.25 | 4.8 | -2.4 |
| 10 | 9.48 | 9.82 | 10.4 | 10.4 | 9.39 | 10.3 | 10.0 | 0.5 | 4.7 | 0.4 |
| 25 | 24.5 | 22.7 | 23.8 | 26.1 | 22.1 | 23.2 | 23.7 | 1.4 | 6.0 | 5.0 |
| 50 | 50.8 | 55.1 | 50.0 | 54.5 | 51.0 | 51.5 | 52.2 | 2.1 | 4.1 | -4.3 |
| 100 | 100 | 96.7 | 97.8 | 106 | 91.9 | 97.2 | 98.3 | 4.6 | 4.7 | 1.7 |