Table 6.
Stability of alfentanil and midazolam in human plasma.
| Analyte | Concentration (ng/ml) | BenchTop (12 hours) | Freeze-thaw (3 times) | Autosampler (72hours) | Long Term (12 months) | ||||
|---|---|---|---|---|---|---|---|---|---|
| CV (%) | Accuracy (%) | CV (%) | Accuracy (%) | CV (%) | Accuracy (%) | CV (%) | Accuracy (%) | ||
| Alfentanil | 1 | 8.4 | 104 | 6.4 | 99.8 | 4.8 | 102 | 8.5 | 95.5 |
| 10 | 6.8 | 97.4 | 7.5 | 96.4 | 5.5 | 105 | 6.4 | 102 | |
| 100 | 4.5 | 102 | 5.6 | 95.6 | 4.9 | 102 | 6.2 | 97.4 | |
| Midazolam | 1 | 7.6 | 96.4 | 6.4 | 93.5 | 8.5 | 102 | 7.8 | 106 |
| 10 | 7.1 | 99.6 | 5.7 | 97.5 | 7.5 | 98.6 | 8.2 | 102 | |
| 100 | 5.4 | 93.6 | 4.9 | 94.6 | 7.1 | 95.8 | 5.1 | 102 | |