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. Author manuscript; available in PMC: 2011 May 9.
Published in final edited form as: J Pharmacol Exp Ther. 2008 May 6;326(2):563–576. doi: 10.1124/jpet.108.136630

Fig. 10. Mecamylamine and DHβE inhibit the locomotor stimulant effect of nicotine.

Fig. 10

Mecamylamine (MEC; 0.1–3.0 mg/kg, sc; left panel) or DHβE (0.1–3.0 mg/kg, sc; right panel) pretreatment was given prior to nicotine (0.4 mg/kg) administration in nicotine-sensitized rats. Points represent the mean (± SEM) total distance traveled (cm) as a function of pretreatment dose. Asterisks indicate a significant difference from the corresponding saline (S) control (*p < 0.05, **p < 0.01, ***p < 0.001).