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. 2011 Apr 4;2:14. doi: 10.3389/fpsyt.2011.00014

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Copyright © 2011 Kiss, Hoffmann, Scott, Kawabe, Milici, Nilsen and Hajós.

This is an open-access article subject to a non-exclusive license between the authors and Frontiers Media SA, which permits use, distribution and reproduction in other forums, provided the original authors and source are credited and other Frontiers conditions are complied with.

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Localized saline administration into the mediodorsal nucleus of the thalamus does not enhance low-delta activity and fails to replicate effects of localized MK-801 administration. (A) A representative spectrogram of ipsilateral mPFC LFP. Insets show characteristic LFP traces from highlighted regions. (B,C) MD-localized saline injection did not influence paired-pulse facilitation. (D) Ongoing LFP high-delta oscillation power significantly (p = 0.0134) decreased after saline injection, however the magnitude of the change was significantly smaller compared to the decreased observed after MK-801 administration (see Figure 8).