Table 1.
Histological changes in mucosa adjacent to ITAC and in controls and comparison to the literature.
| This study | [11] | [12] | [13] | [14] | [15] | [16] | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Tissue sample | Adjacent | Control | Adjacent | Adjacent | Mucosa | Mucosa | Mucosa | Mucosa | ||||||||
| Wood exposure | Yes | No | Yes | No | Yes | No | Yes | Yes | No | Yes | No | Yes* | No | Yes | No | |
| Number of samples | 45 | 6 | 17 | 2 | 10 | 5 | 22 | 144 | 31 | 65 | 68 | 139 | 16 | 113 | 54 | |
| Surface epithelium |
Dysplasia | 6 (13%) | 1 (17%) | 1 (6%) | 0 | 0 (0%) | 0 (0%) | 16 (73%) | 7 (5%) | 1 (3%) | 0 (0%) | 0 (0%) | 37 (27%) | 0 | 14 (12%) | 1 (2%) |
| Cuboidal metaplasia | 25 (56%) | 4 (67%) | 4 (24%) | 1 (50%) | 19 (86%) | 40 (28%) | 5 (16%) | |||||||||
| Squamous metaplasia | 10 (22%) | 2 (33%) | 1 (6%) | 0 | 0 (0%) | 0 (0%) | 5 (23%) | 57 (40%) | 16 (52%) | 40 (61%) | 5 (7%) | 90 (65%) | 2 (13%) | 41 (40%) | 17% | |
| Hyperplasia | 26 (58%) | 1 (17%) | 4 (24%) | 1 (50%) | 59 (41%) | 6 (19%) | 30 (22%) | 1 (6%) | ||||||||
| Intestinal metaplasia | 3 (7%) | 1 (17%) | 0 | 0 | ||||||||||||
|
| ||||||||||||||||
| Seromucinous glands |
Dysplasia | 8 (18%) | 2 (33%) | 0 | 0 | |||||||||||
| Hyperplasia | 14 (31%) | 3 (50%) | 7 (41%) | 0 | ||||||||||||
*Exposure to leather dust.