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. 2011 Mar;4(1):20–26. doi: 10.2478/v10102-011-0005-y

Figure 1.

Figure 1

Effect of SMe1EC2 on endothelium-dependent relaxation of the superior mesenteric artery (SMA) ex vivo. Acetylcholine-induced responses of the phenylephrine (1µmol/l)-precontracted rings of SMA from control rats (C), control rats treated with 10mg/kg SMe1EC2 (C-SMe1EC2), diabetic rats (D), diabetic rats treated with SMe1EC2 (D-SMe1EC2). A – before blockade of eNOS with L-NAME and of prostaglandin synthesis with indomethacin; B – after blockade of eNOS with L-NAME and of prostaglandin synthesis with indomethacin. Data are means±S.E.M. of 8 experiments. ***p<0.001 versus C.